OncoImmunin, Inc.
was founded by Dr. Akira
Komoriya and Dr.
Beverly Packard in 1994. The Company has been issued three U.S.
patents and one Australian patent on its proprietary design for protease
inhibitors and fluorogenic substrates. Multiple new applications as well CIP and
PCT applications are under review.
OncoImmunin, Inc.
has designed, synthesized, validated, and patented a new class of protease
substrates. Unique aspects of these molecules are: (1) incorporation of amino
acid sequence information from both sides of protease cleavage sites (up to ten
amino acid residues), thereby providing not only linear but three-dimensional
specificity for proteases and (2) ability to cross intact cell membranes
enabling measurement and inhibition of intracellular protease activities in
living cells. Exploitation of elements of this latter point form the basis for
OncoImmunin's patented design for the therapeutic delivery of peptide-based
protease inhibitors as well as peptide-based inhibitors of other intracellular
targets in sizes ranging up to twenty amino acids.
The Company, a
graduate of the University of Maryland's Technology Advancement Program, is now
located in Gaithersburg, MD.