Cancer Metastasis Detection

 

 

 Metastasis detection is now possible using OncoImmunin's unique fluorogenic substrates to assay the protease activities associated with metastasis of malignant cells. Examples of current reagents for metastasis analysis are CaDiLux® for the detection of cathepsin D, ElastoLux® for the detection of elastase, and MetastaLuxTM for detection of collagenolytic activity.

As with OncoImmunin’s caspase substrates, CaDiLux® and ElastoLux® cross intact plasma membranes and are therefore able to detect intracellular proteolytic activites in live cells. In contrast, MetastaLuxTM, which contains a sequence found in collagen, is immobilized and can detect cells utilizing collagenolytic activity as they move through a 3-dimensional matrix.

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OncoImmunin, Inc.,
207A Perry Parkway, Suite 6
Gaithersburg, MD 20877
Phone: (301) 987-7881
FAX: (301) 987-7882
email:info@PhiPhiLux.com.com

 

 

 

 

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